On June 22, 2000, UCSC and the other members of the International Human Genome Project consortium
completed the first working draft of the human genome assembly, forever ensuring
free public access to the genome and the information it contains. A few weeks
later, on July 7, 2000, the newly assembled genome was released on the web at
http://genome.ucsc.edu, along with the initial prototype of a graphical viewing tool, the
UCSC Genome Browser. In the ensuing years, the website has grown to include a broad
collection of vertebrate and model organism assemblies and annotations, along with a large
suite of tools for viewing, analyzing and downloading data.
Tools provided on Genome Browser:
-
Genome Browser
interactively visualize genomic data
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BLAT
rapidly align sequences to the genome
-
Table Browser
download data from the Genome Browser database
-
Variant Annotation Integrator
get functional effect predictions for variant calls
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Data Integrator
combine data sources from the Genome Browser database
-
Gene Sorter
find genes that are similar by expression and other metrics
-
Genome Browser in a Box (GBiB)
run the Genome Browser on your laptop or server
-
In-Silico PCR
rapidly align PCR primer pairs to the genome
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LiftOver
convert genome coordinates between assemblies
-
VisiGene
interactively view in situ images of mouse and frogThe following tools and utilities created by the UCSC Genome Browser Group are available for public use:
- Batch Coordinate Conversion (liftOver) - converts genome coordinates and genome annotation files between assemblies. The current version supports both forward and reverse conversions, as well as conversions between selected species.
- DNA Duster - removes formatting characters and other non-sequence-related characters from an input sequence. Offers several configuration options for the output format, including translated protein.
- Protein Duster - removes formatting characters and other non-sequence-related characters from an input sequence. Offers several configuration options for the output format.
- Phylogenetic Tree PNG Maker - creates a PNG image from the phylogenetic tree specification given. Offers several configuration options for branch lengths, normalized lengths, branch labels, legend etc.
- Executable and Source Code Downloads - executable and source code downloads of the Genome Browser, Blat and liftOver.
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